EFFECT OF INITIAL SEEDING DENSITY ON CELL BEHAVIOR-DRIVEN EPIGENETIC MEMORY AND PREFERENTIAL LINEAGE DIFFERENTIATION OF HUMAN IPSCS

Effect of initial seeding density on cell behavior-driven epigenetic memory and preferential lineage differentiation of human iPSCs

Understanding the cellular behavioral mechanisms underlying memory formation and maintenance in human induced pluripotent stem cell (hiPSC) culture provides key strategies for achieving stability and robustness of cell differentiation.Here, we show that changes in cell behavior-driven epigenetic memory of hiPSC cultures alter their pluripotent stat

read more



Relationship between thick or greasy tongue-coating microbiota and tongue diagnosis in patients with primary liver cancer

Tongue diagnosis is a unique aspect of traditional Chinese medicine for diagnosing diseases before determining proper means of treatment, but it also has the disadvantage of relying on the subjective experience of medical practitioners and lack objective basis.The purpose of this article is to elucidate tongue-coating microbiota and metabolic diffe

read more

A systematic review of new advances in the management of mucopolysaccharidosis VI (Maroteaux-Lamy syndrome): focus on galsulfase

Regina P El Dib1, Gregory M Pastores21Department of Surgery, McMaster University, McMaster Institute of Urology, Hamilton, Ontario, Canada; 2Department of Neurology and Pediatrics, New York University School of Medicine, New York, NY, USAIntroduction: Mucopolysaccharidosis type VI (MPS VI, Maroteaux-Lamy syndrome) is an autosomal recessive lysosoma

read more